CITMIC: Estimation of Cell Infiltration Based on Cell Crosstalk

A systematic biology tool was developed to identify cell infiltration via an Individualized Cell crosstalk network. 'CITMIC' first constructed a weighted cell crosstalk network by integrating Cell-target interaction information, biological process data from the Gene Ontology (GO) database, and gene transcriptomic data in a specific sample, and then, it used a network propagation algorithm on the network to identify cell infiltration for the sample. Ultimately, cell infiltration in the patient dataset was obtained by normalizing the centrality scores of the cells.

Version:	0.1.1
Depends:	R (≥ 2.10)
Imports:	fastmatch, igraph, parallel, stats
Suggests:	knitr, rmarkdown
Published:	2024-09-17
DOI:	10.32614/CRAN.package.CITMIC
Author:	Junwei Han [aut, cre, cph], Xilong Zhao [aut]
Maintainer:	Junwei Han <hanjunwei1981 at 163.com>
License:	GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation:	no
CRAN checks:	CITMIC results

Documentation:

Reference manual:	CITMIC.pdf
Vignettes:	CITMIC User Guide (source, R code)

Downloads:

Package source:	CITMIC_0.1.1.tar.gz
Windows binaries:	r-devel: CITMIC_0.1.1.zip, r-release: CITMIC_0.1.1.zip, r-oldrel: CITMIC_0.1.1.zip
macOS binaries:	r-release (arm64): CITMIC_0.1.1.tgz, r-oldrel (arm64): CITMIC_0.1.1.tgz, r-release (x86_64): CITMIC_0.1.1.tgz, r-oldrel (x86_64): CITMIC_0.1.1.tgz
Old sources:	CITMIC archive

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