benchdamic
Benchmark of differential abundance methods on microbiome data
Bioconductor version: Release (3.20)
Starting from a microbiome dataset (16S or WMS with absolute count values) it is possible to perform several analysis to assess the performances of many differential abundance detection methods. A basic and standardized version of the main differential abundance analysis methods is supplied but the user can also add his method to the benchmark. The analyses focus on 4 main aspects: i) the goodness of fit of each method's distributional assumptions on the observed count data, ii) the ability to control the false discovery rate, iii) the within and between method concordances, iv) the truthfulness of the findings if any apriori knowledge is given. Several graphical functions are available for result visualization.
Author: Matteo Calgaro [aut, cre] 
, Chiara Romualdi [aut] , Davide Risso [aut] , Nicola Vitulo [aut]
Maintainer: Matteo Calgaro <mcalgaro93 at gmail.com>
citation("benchdamic")):
Installation
To install this package, start R (version "4.4") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("benchdamic")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
| Reference Manual | |
| NEWS | Text |
Details
| biocViews | DifferentialExpression, Metagenomics, Microbiome, MultipleComparison, Normalization, Preprocessing, Software |
| Version | 1.11.1 |
| In Bioconductor since | BioC 3.14 (R-4.1) (3 years) |
| License | Artistic-2.0 |
| Depends | R (>= 4.3.0) |
| Imports | stats, stats4, utils, methods, phyloseq, TreeSummarizedExperiment, BiocParallel, zinbwave, edgeR, DESeq2, limma, ALDEx2, corncob, SummarizedExperiment, MAST, Seurat, ANCOMBC, mixOmics, lme4, NOISeq, dearseq, MicrobiomeStat, Maaslin2, GUniFrac, metagenomeSeq, MGLM, ggplot2, RColorBrewer, plyr, reshape2, ggdendro, ggridges, graphics, cowplot, grDevices, tidytext |
| System Requirements | |
| URL | |
| Bug Reports | https://github.com/mcalgaro93/benchdamic/issues |
See More
| Suggests | knitr, rmarkdown, kableExtra, BiocStyle, magick, SPsimSeq, testthat |
| Linking To | |
| Enhances | |
| Depends On Me | |
| Imports Me | |
| Suggests Me | |
| Links To Me | |
| Build Report | Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
| Source Package | |
| Windows Binary (x86_64) | |
| macOS Binary (x86_64) | |
| macOS Binary (arm64) | benchdamic_1.11.1.tgz |
| Source Repository | git clone https://git.bioconductor.org/packages/benchdamic |
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/benchdamic |
| Bioc Package Browser | https://code.bioconductor.org/browse/benchdamic/ |
| Package Short Url | https://bioconductor.org/packages/benchdamic/ |
| Package Downloads Report | Download Stats |