library(serosv)
Refer to Chapter 7.1
Proposed model
Within the local polynomial framework, the linear predictor \(\eta(a)\) is approximated locally at one particular value \(a_0\) for age by a line (local linear) or a parabola (local quadratic).
The estimator for the \(k\)-th derivative of \(\eta(a_0)\), for \(k = 0,1,…,p\) (degree of local polynomial) is as followed:
\[ \hat{\eta}^{(k)}(a_0) = k!\hat{\beta}_k(a_0) \]
The estimator for the prevalence at age \(a_0\) is then given by
\[ \hat{\pi}(a_0) = g^{-1}\{ \hat{\beta}_0(a_0) \} \]
The estimator for the force of infection at age \(a_0\) by assuming \(p \ge 1\) is as followed
\[ \hat{\lambda}(a_0) = \hat{\beta}_1(a_0) \delta \{ \hat{\beta}_0 (a_0) \} \]
Fitting data
<- mumps_uk_1986_1987
mump <- mump$age
age <- mump$pos
pos <- mump$tot
tot <- pos/tot y
Use plot_gcv()
to show GCV curves for the nearest
neighbor method (left) and constant bandwidth (right).
plot_gcv(
age, pos, tot,nn_seq = seq(0.2, 0.8, by=0.1),
h_seq = seq(5, 25, by=1)
)
Use lp_model()
to fit a local estimation by
polynomials.
<- lp_model(age, pos = pos, tot = tot, kern="tcub", nn=0.7, deg=2)
lp plot(lp)