Reproducible and automated analysis of multiplex bead assays such as CBA (Morgan et al. 2004; <doi:10.1016/j.clim.2003.11.017>), LEGENDplex (Yu et al. 2015; <doi:10.1084/jem.20142318>), and MACSPlex (Miltenyi Biotec 2014; Application note: Data acquisition and analysis without the MACSQuant analyzer; <https://www.miltenyibiotec.com/upload/assets/IM0021608.PDF>). The package provides functions for streamlined reading of fcs files, and identification of bead clusters and analyte expression. The package eases the calculation of standard curves and the subsequent calculation of the analyte concentration.
Version: | 0.5.0 |
Depends: | R (≥ 4.3) |
Imports: | cluster, dplyr, drc, fpc, ggplot2, mclust, purrr, tibble, tidyr, yaml, rlang |
Suggests: | spelling, gridExtra, hexbin, knitr, rmarkdown, stringr, testthat |
Published: | 2023-06-16 |
DOI: | 10.32614/CRAN.package.beadplexr |
Author: | Ulrik Stervbo [aut, cre] |
Maintainer: | Ulrik Stervbo <ulrik.stervbo at gmail.com> |
BugReports: | https://gitlab.com/ustervbo/beadplexr/-/issues |
License: | MIT + file LICENSE |
URL: | https://gitlab.com/ustervbo/beadplexr |
NeedsCompilation: | no |
Language: | en-US |
Citation: | beadplexr citation info |
Materials: | README NEWS |
CRAN checks: | beadplexr results |
Reference manual: | beadplexr.pdf |
Vignettes: |
beadplexr with CBA and MACSPlex assays Analysis of LEGENDplex data with 'beadplexr' Preparing flow-data for use with with 'beadplexr' |
Package source: | beadplexr_0.5.0.tar.gz |
Windows binaries: | r-devel: beadplexr_0.5.0.zip, r-release: beadplexr_0.5.0.zip, r-oldrel: beadplexr_0.5.0.zip |
macOS binaries: | r-release (arm64): beadplexr_0.5.0.tgz, r-oldrel (arm64): beadplexr_0.5.0.tgz, r-release (x86_64): beadplexr_0.5.0.tgz, r-oldrel (x86_64): beadplexr_0.5.0.tgz |
Old sources: | beadplexr archive |
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